Science Policy For All

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Posts Tagged ‘antibiotics

Science Policy Around the Web – May 18, 2015

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By: Amanda Whiting, Ph.D.

Agriculture and Food Policy

Food industry braces for Obama trans fat ban

The Food and Drug Administration (FDA) is expected to announce its final determination on the use of partially hydrogenated oils (or trans fats) in food products as early as next week. The announcement is expected to ban the use of trans fats. This potentially marks a final step in removing artificial trans fats from the American diet, a move that began in 2013 when the Obama administration issued a tentative determination stating that partially hydrogenated oils are not generally regarded as safe (GRAS). Partially hydrogenated oils are created when unsaturated liquid oils are exposed to hydrogen, which reduces their unsaturation and creates solid fats that improve food product texture and shelf life. Consumption of trans fats have been linked to cardiovascular disease and their removal could “prevent 20,000 heart attacks and some 7,000 deaths” according to FDA estimates, said Sam Kass, the former senior adviser for nutrition at the White House and executive director of Let’s Move!, to Politico. While the potential health benefits of such a policy are easily apparent, there are other repercussions to consider with a policy change such as this. Trans fats have been used in a myriad of smaller applications, such as in the sprinkles on cupcakes to prevent color leaching, to prevent baked goods from sticking to equipment, and to stabilize flavors in food products, that may not have been well considered by the FDA. Food manufacturers will need tweak their recipes and/or find alternative substances to fill the void left by a trans fat ban. In the past, they have turned to palm oil, though there are environmental concerns over rainforest deforestation to harvest the palm oil. Getting rid of trans fats is not a bad idea in terms of public health – let’s hope that its alternative does not end up having an unintended detrimental effect elsewhere. (Helena Bottemiller Evich, Politico)

Antibiotic resistance

Guarantee drug companies a profit to develop new antibiotics, U.K. report says

With the increasing, widespread and global appearance of antibiotic resistant infections, the need to develop new potent antibiotics to tackle these threats is quite clear. Once developed however, in order to prevent resistance from developing to the new drugs, their use – and in our current economic model, their sales – must be restricted and limited. This presents drug companies with a problem, since the high cost of drug research and development is often driven and funded with an eye on the potential future sales of a drug. This makes it highly economically undesirable for a drug company to spend resources to develop a drug that must then be restricted, despite the very great worldwide need for such drugs. A report commissioned by the government of the United Kingdom, seeks to fix this problem. In the report, it is suggested that global governments “unite to offer multibillion-dollar incentives for drug developers, and pharmaceutical companies should pool their billions in support of early-stage research.” Most interestingly, the report suggests a way to incentivize drug development without encouraging overuse by “de-linking” a drug company’s profits from the drug’s sales. Specific examples of how this could be accomplished include having a “designated global body” buy the rights to a new pharmaceutical (at $2-3 billion per antibiotic) and then carefully manage the worldwide supply, or having a company retain the rights to the drug but receive a “bonus” for developing and introducing it to market, while being patient with overall (rather than initial blockbuster) sales. While this would take worldwide cooperation, aligning financial incentives for drug companies with the needs public health via a unifying policy could help kick-start drug development where we need it most. (Kelly Servick, ScienceInsider)

Federal Funding

Key House Republican says 70% of NSF’s research dollars should go to “core” science—not geo or social research

Two out of the six research directorates at the National Science Foundation (NSF) have been targeted to not receive any additional funds in the 2016 federal spending bill. The current spending bill allots an additional $50 million to the overall NSF budget, much smaller than the total $379 million (or 4.3% increase) requested. The markup of the House spending bill from the Commerce, Justice, and Science (CJS) subcommittee would allow the NSF to spread the additional $50 million in funds only in areas that have been deemed “pure sciences” – namely, biology, computing, engineering, and math and physical sciences. The bill prevents NSF from funding research in geoscience and the social and behavioral sciences. Both Representative John Culberson (R–TX), chair of the CJS subcommittee, and Representative Lamar Smith (R–TX), chair of the science committee who introduced the America COMPETES Act to set NSF policies, say they support the NSF and simply want to make sure what it funds is in the “national interest.” That is all well and good, but what is in the “national interest” today may not be where the groundbreaking research of tomorrow is born. Scientific research is increasingly breaking out of such siloed classifications and into multidisciplinary fields and collaborative discovery that require inputs from all areas. While Rep. Culberson may favor funding only the “hard sciences,” understanding our own home planet and our human-to-human interactions are also areas worthy of study and research. (Jeffrey Mervis, ScienceInsider)

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May 18, 2015 at 9:00 am

Science Policy Around the Web – March 24, 2015

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By: Courtney Pinard, Ph.D

Open Access

NSF unveils plan to make scientific papers free

The National Science Foundation (NSF) unveiled a plan last week that will require their grantees to make their peer-reviewed research papers freely available within 12 months of publication. This plan comes two years after the White House Office of Science and Technology Policy ordered U.S. federal science agencies to devise their own public-access policies. According to the plan, archives of full-text articles will be available on the publisher’s website. The push for public-access policies by some scientists and activists has been happening since the late 1990s with the National Institutes of Health (NIH) leading the effort with PubMed Central repository. Many publishers critical of repositories like PubMed Central say that public access policies infringe on their copyright and decrease their revenues. In response to these concerns, NSF has decided to work with the Department of Energy to create a system called PAGES (Public Access Gateway for Energy and Science). PAGES will contain abstracts, authors, and other metadata, but not the full-text paper. Instead, PAGES will provide a link to the full-text paper on the publisher’s website. In the future, NSF may allow open access to full-text papers through other repositories. (Jocelyn Kaiser, ScienceInsider)

Infectious Disease

Is Tuberculosis Still a Risk?

Tuberculosis is a widespread, and in many cases fatal, infectious disease caused by various strains of mycobacteria. Tuberculosis (TB) was once the top killer in the U.S. during the 19th century. With the advent of antibiotics, TB cases have steadily declined. In 2013, for example, 9,588 cases were reported in the U.S. Because of antibiotic resistant strains, there has been a surge in the number of people falling sick with TB in recent decades. Just last week, 27 people tested positive for TB at Olathe Northwest High School in Olathe, Kansas after a single case prompted testing. Due to the strength of their immune systems and access to proper antibiotics, none of these 27 people had symptoms, nor were they contagious. Without the correct treatment, however, more than 80% of people die from the infection. In fact, TB is the second leading cause of death in adults world-wide after HIV, and affects 1 million children each year. Two-thirds of the drug-resistant cases are found in the BRICS countries – Brazil, Russia, India, China and South Africa. Health policy officials in these countries started working on a TB treatment access plan more than two years ago, but little progress has been made. According to a report by the World Health Organization (WHO), three million people developing tuberculosis in BRICS countries are missed by national notification systems each year and only a fraction of cases are being treated. The WHO report emphasized the need to improve vulnerable populations’ access to quality tuberculosis care in low- to middle-income countries. Maybe, one day, TB-infected individuals in BRICS countries will have similar access to TB medical testing and treatment as those in Olathe, Kansas have. (Jacob Creswell, WHO; Dr. Salmaan Keshavjee, NPR)

Global Health and Agriculture

For the love of pork: Antibiotic use on farms skyrockets worldwide

As the developing world becomes richer, more and more people are consuming meat. Increased meat production will lead to the skyrocketing use of antibiotics, according to a study published last week in the Proceedings of the National Academy of Sciences. The study estimates that of the 228 countries who use antibiotics in livestock, total consumption will increase 67% from 63,151 tons in 2010 to 105,596 tons by 2030. The authors suggest that a huge rise in farm drug use will be especially prevalent in middle-income countries, where there is no regulation of antibiotic use on farms. That being said, although the United States Food and Drug Administration has made efforts to limit antibiotic use, critics say U.S. policies passed so far support “voluntary cooperation,” not binding regulation. (Michaeleen Doucleff, NPR)

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Written by sciencepolicyforall

March 24, 2015 at 9:00 am

Science Policy Around the Web – November 16, 2011

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By:  Rebecca Cerio

Our weekly linkpost, bringing you interesting and informative links on science policy issues buzzing about the internet.

Alarming Pattern of Antibiotic Use Emerges – Antibiotic use is up, particularly in certain parts of the country like the Southeast.  Is this use responsible, or are we overprescribing antibiotics for illnesses that they cannot treat (like colds and the flu)?  As antibiotic overuse can lead to pathogens developing antibiotic resistance, the Extending the Cure project suggests that the driving forces behind increased antibiotic use should be investigated.  (press release via the Center for Disease Dynamics, Economics & Policy, by Andrea Titus)

Why Science Majors Change Their Minds (It’s Just So Darn Hard) –  “…middle and high school students are having most of the fun, building their erector sets and dropping eggs into water to test the first law of motion. The excitement quickly fades as students brush up against the reality of what David E. Goldberg, an emeritus engineering professor, calls “the math-science death march.” Freshmen in college wade through a blizzard of calculus, physics and chemistry in lecture halls with hundreds of other students. And then many wash out.”  (via The New York Times, by Christopher Drew)

Switching from Intravenous to Oral Medications Can Save Millions – Researchers at Johns Hopkins Hospital found that switching hospitalized patients from an intravenous to an equivalent oral version of just four expensive medications could save over a million dollars a year.  They suggest that widespread education and reminders to doctors to prescribe the cheaper oral form of medications to eligible patients could save billions in health care costs annually. (via, by Stephanie Desmond)

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Written by sciencepolicyforall

November 16, 2011 at 12:46 pm


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